Shingles vaccine reduces risk of heart disease by 23%, study of one million people finds

CNN - May 9th, 2025

A new study published in the European Heart Journal by South Korean researchers involving over one million participants suggests that the shingles vaccine, traditionally used to prevent the varicella-zoster virus, may also significantly reduce the risk of cardiovascular issues such as heart disease and stroke. The study found a 23% lower risk of cardiovascular disease in individuals aged 50 and older who were vaccinated, with the most notable effects observed up to eight years post-vaccination. These benefits appeared particularly pronounced in males, those under 60, and individuals with unhealthy lifestyles, such as chronic smokers or drinkers.

The implications of the study are profound, suggesting a broader role for vaccinations in public health beyond mere protection from infectious diseases. The research highlights that preventing shingles could mitigate inflammation in blood vessels and subsequent cardiovascular risks. Despite the promising findings, more targeted research is necessary to establish a direct causal link between the vaccine and reduced cardiovascular events. Additionally, the study used an older version of the shingles vaccine, which has been largely replaced by a more effective one, warranting further exploration of potential health benefits across vaccine types. Researchers emphasize the need for diverse study populations to understand the full scope of the vaccine's benefits.

Heart Disease Shingles Vaccine Stroke Varicella Zoster Virus European Heart Journal Hayeon Lee Dr. Sharon Curhan Dr. Pascal Geldsetzer Vaccination Benefits Inflammation Cardiovascular Health

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RATING

7.8

Fair Story

Consider it well-founded

The article provides a well-rounded and generally accurate overview of the potential cardiovascular benefits of the shingles vaccine, based on a recent study. It effectively communicates complex medical information in an accessible manner, supported by credible sources and expert opinions. The story is timely and relevant, addressing a public health topic of significant interest. While the article acknowledges the need for further research and presents a balanced view, it could improve by offering more transparency about the study's methodology and including a wider range of perspectives. Overall, the article succeeds in informing readers about an important health issue while maintaining clarity and engagement.

Accuracy

The article presents factual claims that are largely supported by the study findings published in the European Heart Journal. It accurately reports that the shingles vaccine is associated with a 23% reduction in the risk of cardiovascular disease, based on a study involving over one million people. The story correctly notes the potential mechanisms by which shingles can increase heart disease risk, such as inflammation in blood vessels and nerve damage. However, it does not emphasize enough the need for further research to establish causality, which is a limitation mentioned in the original study. The reference to the replacement of the live zoster vaccine with Shingrix is accurate, but the story could have provided more details on the differences between these vaccines.

Balance

The article provides a balanced view by including perspectives from multiple experts, such as Dr. Sharon Curhan and Dr. Pascal Geldsetzer, who discuss the study's limitations. It acknowledges the need for further research and the observational nature of the study, which helps to present a nuanced view. However, the article could have included more perspectives from those who might be skeptical of the vaccine's broader health benefits or those who emphasize the importance of randomized controlled trials over observational studies.

Clarity

The article is well-structured and uses clear, accessible language to convey complex medical information. The logical flow of information helps readers understand the potential health benefits of the shingles vaccine and the study's limitations. The use of expert quotes and explanations of medical terms like 'varicella-zoster virus' and 'cardiovascular disease' enhance comprehension. Overall, the article maintains a neutral tone and presents information in an easily digestible format.

Source quality

The article cites credible sources, including the European Heart Journal and experts from reputable institutions such as Brigham and Women’s Hospital and Stanford University. The inclusion of expert opinions adds authority to the reporting. However, the article could have benefitted from direct quotes from the study authors or additional context from the European Heart Journal publication to enhance source attribution.

Transparency

The article provides a clear explanation of the study's findings and mentions the limitations related to the observational nature of the research. It also discusses the need for further studies in diverse populations. However, it could be more transparent about the methodology used in the study, such as how data was collected and analyzed. Additionally, more information on potential conflicts of interest or funding sources for the study would improve transparency.